Wikinventia — Atlas of discoveries and inventions · Industrial Age

Ventricular Fibrillation — John McWilliam

1889 AD · Transmission: Silenced
MedicineBiologyDiscoveryBritish

In 1889, Scottish physiologist John McWilliam published in the British Medical Journal the first systematic description of ventricular fibrillation as the mechanism of sudden cardiac death, and experimentally demonstrated that weak electric currents could induce it in mammalian hearts. His work established that fibrillation — not simple cardiac arrest — was the underlying cause of sudden death by electricity. Prévost and Batelli explicitly cited McWilliam in 1899 as the starting point for their experiments on VF reversal. His work remained little recognized for decades; clinical cardiology took over half a century to translate this finding into therapy.

InstitutionUniversity of Aberdeen
Historical regionScotland, United Kingdom
Primary sourceMcWilliam, J. A. — "Fibrillation of the Ventricles" (British Medical Journal, vol. 1, no. 1462, pp. 6-10, 1889)
Secondary sourcePMC/NIH
Original languageEnglish
View this entry in the interactive atlas → View in graph →